WuXi Medical Device Platform offers the following In Vivo assays to semi-quantitatively evaluate the antimicrobial activity of medical devices and their components, or other materials with antimicrobial product features or that have been treated with antimicrobial agents. Many of the standard test methods listed here may be modified to include different or additional organisms, or accommodate different or additional exposure times based on product application, claims and characteristics, the activity of the medical device and its components, antimicrobial product features or other materials treated with antimicrobial agents.
Antimicrobial Efficacy (AME) – In Vivo Studies
Each antimicrobial efficacy study is custom designed, using clinically relevant bacterial strains and several implant and infection-delivery methodologies to produce a consistent and non-lethal In Vivo device infection. Analyses of infection include semi-quantitative assessment of remaining viable bacteria from device and surrounding tissue, imaging, and identification of viable bacterial strain from the resulting infection.