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Bacterial Endotoxin (LAL) Tests

Pyrogens are fever-producing materials that most often originate from Gram-negative bacterial cell walls, but can also originate as leachates from some chemicals and materials. Pyrogens from bacterial cell walls (the most commonly encountered type of pyrogen) are referred to as bacterial endotoxins and are readily detected by Limulus Amebocyte Lysate (LAL) testing systems.

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Validation of the inhibition or enhancement properties of materials on the test system.
Quantitative determination of endotoxin level for finished devices or other materials.
Endotoxin testing of water system samples or other non-biological liquids.
Quantitative assay for the detection of gram-negative bacterial endotoxin. The presence of the endotoxin causes a color change and the solution becomes yellow.
Quantitative assay for the detection of gram-negative bacterial endotoxin. The presence of the endotoxin causes the lysate to gel and the solution to become cloudy or opaque.