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Pyrogenicity Testing (In Vivo)

Pyrogenicity tests determine the potential of materials, extracts, and/or a finished device to induce a pyrogenic (fever) response from sources other than endotoxin.

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The test articles are injected to determine a significant increase in body temperature compared to the control article.
The test articles are injected to determine a significant increase in body temperature compared to the control article.

MHLW Testing

MHLW Materials Mediated Rabbit Pyrogen
Pyrogenicity tests determine the potential of materials, extracts, and/or a finished device to induce a pyrogenic (fever) response from sources other than an endotoxin.