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Irritation Testing

Irritation tests assess the localized reaction of tissues to device materials or extracts. The selection of a test method is based on intended patient contact type.

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Test material solution or an extract of a device injects under the skin to test the possible irritancy of the test article compounds.
Test material solution or an extract of a device injects under the skin to test the possible irritancy of the test article compounds.
Materials that comes in direct or indirect contact with mucosal tissue received repeated administration of dose to observe possible irritation.
This test is performed to assess the potential topical irritation from acute exposure or device material.
This assay provides a quantitative method to screen materials for potential skin irritation potential.

MHLW Testing

MHLW Intracutaneous Irritation Test
The purpose of this test is to determine if chemicals that may leach or be extracted from the test material are capable of causing local irritation in the dermal tissues.